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MUMBAI NABICON RESEARCH AWARD 2013
Year : 2014  |  Volume : 22  |  Issue : 1  |  Page : 3-9

Scar biology: Fibroblast the key modulator


1 Department of Burns and Plastic Surgery, CHILDS Trust Medical Research Foundation, Kanchi Kamakoti CHILDS Trust Hospital, Chennai, India
2 Research Office, CHILDS Trust Medical Research Foundation, Kanchi Kamakoti CHILDS Trust Hospital, Chennai, India
3 Consultant Plastic Surgeon, Kanchi Kamakoti CHILDS Trust Hospital, Nungambakkam, Chennai, India
4 Department of Burns and Plastic Surgery, Chennai Medical College and Research Institute, Thiruchirapalli, Tamilnadu, India

Correspondence Address:
Mathangi K Ramakrishnan
H.O.D, Department of Burns and Plastic Surgery, CHILDS Trust Medical Research Foundation, Kanchi Kamakoti CHILDS Trust Hospital, Chennai
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-653X.146990

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Introduction: Normal wound repair of human skin involves several well-orchestrated phases, which are overlapping, yet distinct in their own way. This presentation aims to define, identify, and classify scars, irrespective of the etiology, describe the methods available to differentiate the various types of scar, and describe the current management strategies available to prevent scar formation. From our studies we conclude that for a good scar outcome early intervention during the evolution of wound healing is required. Meticulous surgery is also essential. Various interventions could be with drugs, chemicals, growth factors, or ionizing radiation. Future holds for continued research in cellular signals.


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