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Year : 2011  |  Volume : 19  |  Issue : 1  |  Page : 70-73

Prognostic importance of condition of blood vessels in burn wounds

Department of Pathology, Jawaharlal Nehru Medical College, A.M.U., Aligarh, India

Correspondence Address:
A H Khan
Department of Plastic Surgery, Jawaharlal Nehru Medical College, A.M.U, Aligarh
A H Khan
Department of Plastic Surgery, Jawaharlal Nehru Medical College, A.M.U, Aligarh
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Source of Support: None, Conflict of Interest: None

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Background: The pathophysiologic alterations involving the vascular system of the burn wounds are of crucial importance. They can thus be used to study and predict the clinical outcome of these patients. Aims and objectives: The study was conducted to ascertain the histopathological changes in blood vessels in and near the burn wounds and correlate these with morbidity and mortality of the patient including relation with burn wound infections Material and methods: The present study was conducted on 56 in-patients with burns involving 30% total body surface area (TBSA). Biopsies were taken from the burn wounds on first instance and subsequently according to relevant signs and symptoms. A total of 72 biopsies were performed. Histopathological examination with particular attention to blood vessels as well as microbiological cultures was performed on the biopsies. These findings were correlated. Observation: Out of the 72 biopsies observed, 39 (54.16%) showed congestion of the blood vessels. Thrombosis was seen in 9 (12.5%) biopsies, and this finding heralded the onset of disseminated intravascular coagulation and septicemia in the patients. Biopsies from cases with massive destruction of tissues showed unremarkable vessels (17 i.e. 23.61%). Other important finding was fibrinoid necrosis which was seen in 11 biopsies (15.27%) and this was associated with uncontrolled burn wound infection. Conclusion: The study showed that congestion of the vessel was the commonest finding in the biopsies while thrombi were associated with a poor prognosis. Other important finding was fibrinoid necrosis which correlated with uncontrolled wound infection.

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